Tuberculosis (TB) is a global problem made more serious by challenges associated with diagnosis and identification of drug resistance. A major challenge is quickly identifying the presence of TB causing bacteria in a patient’s sample. Conventionally, for the most accurate diagnoses, samples are cultured for six weeks before being tested and while n...

Developing potential new drugs often involves costly laboratorybased evaluations and drug discovery is currently based on finding new molecules similar to existing ones with known properties. Key to new drug development is an improved understanding of how existing drugs destroy microbe cells and how this relates to the drug’s bio-molecular structur...