Collaborative Research Projects
Current projects
Fundamental protein metrology to support the definition of measurands, analytical targets, and their associated measurement uncertainty
ProMET
Proteins, which on a primary level consist of a sequence of amino acids, undergo complex folding mechanisms until they have reached their final struct...
Manufacturing of commutable calibrators and quality control materials for standardisation and post-market surveillance of IVD tests
COMET
In vitro diagnostic tests are commonly used in medicine to measure biomarker concentrations, which will influence medical diagnosis and treatment opti...
Metrology for innovative nanotherapeutics
MetrINo
Until 2050, the median age is estimated to increase by 4.5 years in Europe, resulting in increased strain on the healthcare system. Novel treatment me...
Metrology for genomic profiling to support early cancer detection and precision medicine
GenomeMET
In Europe, cancer caused 1.26 million deaths in 2020, and the number of deaths caused by cancer is expected to increase by 32 % by 2040.
The EU Beati...
Standardisation of measurements of neurodegenerative disease biomarkers
NEuroBioStand
Neurodegenerative diseases (NDD) pose a significant economic and social burden in Europe, with Alzheimer’s disease (AD) and Parkinson’s disease having...
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Completed projects
New underpinning standards for improved bio-analytical measurement in infectious diseases
Bio-stand 2
Antibiotic resistant bacteria could contribute to 10 million deaths per year by 2050, not including those dying from viral infections. Nucleic acid (N...
Standardisation of concentration measurements of extracellular vesicles for medical diagnoses
METVES II
Early diseases diagnosis is generally advantageous for patients compared to late-stage interventions, providing better clinical outcomes. In addition,...
Metrology to enable rapid and accurate clinical measurements in acute management of sepsis
SEPTIMET
Sepsis is a life-threatening complication of infections, responsible for about 700,000 deaths a year in Europe, and six million worldwide. To improve ...
Metrology and innovation for early diagnosis and accurate stratification of patients with neurodegenerative diseases
NeuroMET2
Neurodegenerative diseases (NDDs) are a major health challenge for society; over 9.9 million new cases of dementia are identified worldwide each year,...
Providing the measurement infrastructure to allow quantitative diagnostic methods for biomarkers of coronary heart diseases
CardioMet
Heart diseases are a major healthcare challenge in the EU. Cardiovascular disease, for instance, presents around 11 million new cases a year and is a ...
New underpinning standards for improved bio-analytical measurement in Biotechnology & In vitro Diagnostics
Bio-stand
The German standards institute DIN has recognised that the traceable measurement of biomolecules is a key problem in many sectors, as well as fundamen...
Quantitative measurement and imaging of drug-uptake by bacteria with antimicrobial resistance
MetVBadBugs
In Europe, antimicrobial resistance is responsible for around 25 000 deaths a year with annual treatment and social costs estimated at around €1.5 bil...
Innovative measurements for improved diagnosis and management of neurodegenerative diseases
NeuroMet
Neurodegeneration is an incurable, debilitating process inflicting a growing medical and economic toll on society and Alzheimer’s disease (AD) and Par...
Novel materials and methods for the detection, traceable monitoring and evaluation of antimicrobial resistance
AntiMicroResist
Bacterial resistance to antibiotic treatments is responsible for around 33,000 deaths a year in Europe. These deaths include those due to bacteria tha...
Metrological characterisation of micro-vesicles from body fluids as non-invasive diagnostic biomarkers
MetVes
Extracellular vesicles, or EV, are cell fragments present in body fluids, such as blood and urine. They are different in patients and healthy people s...
Metrology for the characterisation of biomolecular interfaces for diagnostic devices
BioSurf
Diagnosing and managing disease is increasingly reliant upon the detection and measurement of biomarkers on a materials surface. In-vitro diagnostic d...
Metrology for biomolecular origin of disease
BiOrigin
Diseases are becoming increasingly resistant toantibiotics, limiting our ability to treat certain patients. Developing new antibiotics is costly and t...
Metrology for monitoring infectious diseases, antimicrobial resistance, and harmful micro-organisms
INFECT-MET
Respiratory tract infections such as pneumonia, influenza and tuberculosis account for almost 50 % of all deaths from infections. Accurate and rapid...
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